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Both GPR A and GPR are located on
2022-07-01

Both GPR109A and GPR81 are located on chromosome 12q24 [3] and mediate anti-lipolytic effects through coupling to Gi-type G proteins [17]. It is important to note that with the recent deorphanization of these receptors, there has been a recommendation to the International Union of Basic and Clinical
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Cichlasoma dimerus as most teleost fish species
2022-07-01

Cichlasoma dimerus, as most teleost fish species, present neurons expressing GnRH3 (Pandolfi et al., 2005). As in most nucleoside analogs species, the neurons expressing GnRH3 are mainly located in the NOR, although few neurons were detected in the olfactory bulb, ventral telencephalon and the POA
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BI 2536 Little is known about the endocrinological control o
2022-07-01

Little is known about the endocrinological control of reproduction in polychaetes. In vertebrates, gonadal maturation is regulated by the hypothalamo-pituitary-gonadal axis. GnRH, GTHs, and steroid hormones are involved in this axis (see Okubo and Nagahama, 2008). In two polychaete species, Perinere
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Recognition and Repair of DNA Damage DNA
2022-07-01

Recognition and Repair of DNA Damage DNA is a reactive molecule that is continually challenged by both endogenous and exogenous insults 1., 2.. Cellular metabolites and their byproducts, environmental toxins, and radiation alter the chemical structure of DNA, producing a wide spectrum of DNA damage
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Although side effects as paresthesia due to the application
2022-07-01

Although side effects as paresthesia due to the application of β-alanine are known, a study in 2006 pointed out that there are no clinical (biochemical or hematological) changes after a long-term supplementation with β-alanine. In 2015, the International Society of Sports Nutrition rejected any argu
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DIDS br Discussion The present study showed that the
2022-07-01

Discussion The present study showed that DIDS the factors of pre-exposure and glutamate drug injections might affect the total latency time. However, the factor of sex did not affect the total latency time. The results indicate that the glutamate system and pre-exposure, but not sex, influence f
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br Discussion The present study showed that the
2022-07-01

Discussion The present study showed that AGI5198 the factors of pre-exposure and glutamate drug injections might affect the total latency time. However, the factor of sex did not affect the total latency time. The results indicate that the glutamate system and pre-exposure, but not sex, influence
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br Conclusion br Conflict of
2022-07-01

Conclusion Conflict of interest Acknowledgments This work was supported by an NRF grant (2016R1A2B4011196) from the Korea Research Foundation. Introduction Thymic epithelial tumors are rare, but they are the most common primary neoplasm of the thymus and of the anterosuperior mediastinu
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The dorsal horn of the spinal cord shows a high
2022-07-01

The dorsal horn of the spinal cord shows a high density of Ca2+-permeable AMPA receptors, particularly in the superficial spinal laminae (laminae I and II), where primary afferents carrying nociceptive and thermoreceptive inputs terminate and synapse on spinal second-order neurons (Engelman et al.,
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The primary requirements of an
2022-07-01

The primary requirements of an ideal bioprobe for glucose transporter-mediated bioimaging include high specificity, sensitivity as well as low cytotoxicity [18]. According to these concepts, we recently reported the simple amide linked glycoconjugates which containing cyanine fluorophores (Cy3 and C
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Next the effects of a phenyl group
2022-07-01

Next, the effects of a phenyl group at the 3- and 4-positions of the furan on GCGR affinity were investigated (). Surprisingly, despite the lack of a 4-phenyl group at the furan, compound exhibited almost the same GCGR affinity as compound . On the other hand, when the phenyl group at the 3-position
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How do myofibroblast sources compare
2022-07-01

How do myofibroblast sources compare between bone marrow and other organs? Perivascular Butaprost with MSC properties significantly contribute to fibrosis in muscle, fat, skin, heart, kidney, lung, and liver (reviewed in Iwayama et al., 2015) and activate Gli1 in many of these organs (Kramann et al.
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tandospirone br Mechanisms of gap junction
2022-07-01

Mechanisms of gap junction internalization: disaggregation, endocytosis and annular gap junctions It has been clearly shown that gap junction internalization can occur by a distinctive mechanism where one cell internalizes an entire gap junction via formation of double membrane structure termed a
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The GAL also modified HT system Millon et al Using
2022-06-30

The GAL(1–15) also modified 5-HT system (Millon et al., 2015). Using a rat medullary raphe-derived cell line RN33B, we observed that GAL(1–15) significantly decreased the 5-HT immunoreactivity in the RN33B Cyanine 3-dUTP mg (p Conclusion All these data emphasized the role of GAL and its N-Termina
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br Pathological consequences of disruption in the GABA T cur
2022-06-30

Pathological consequences of disruption in the GABA/T current equilibrium This issue has been particularly investigated in the context of absence seizures. These seizures are non-convulsive epileptic attacks present in many generalized genetic epilepsies that are characterized by a sudden and re
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