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SMAD plays a pivotal role in the
2018-10-25
SMAD4 plays a pivotal role in the pathological progression of vascular disorder (Zhang et al., 2016). SMAD4, a member of Smad family, is a central mediator in the canonical TGF-β signaling. It regulates biological processes important for the pathogenesis of TAAD, such as SMCs migration and prolifera
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Adolescents in this study averaged over h
2018-10-25
Adolescents in this study averaged over 8h of sleep per night, which is similar to what has been obtained in other studies with this age group (Wolfson and Carskadon, 1998; Fuligni and Hardway, 2006) and is close to the number of hours recommended for adolescents (Wolfson and Carskadon, 1998). Yet,
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Introduction Psoriasis is a chronic inflammatory dermatologi
2018-10-25
Introduction Psoriasis is a chronic inflammatory dermatological disorder that impairs the quality of life of patients both physically and psychologically. Its prevalence is estimated to be 2%, and the total rate of psoriasis in children younger than 18 years old, including about 3.5–16% infantile p
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br Video data reduction To measure
2018-10-25
Video data reduction To measure the FMY in a cost-effective manner, the testing team leveraged a new developmental technology called the Automated Launch Video Analysis (ALVA) method [7]. The ALVA system works by capturing video from two opposing high speed camera systems (with rotating views) lo
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buy ANA 12 La corriente del psicoan lisis que se desarroll e
2018-10-25
La corriente del psicoanálisis que se desarrolló en Estados Unidos se apegó buy ANA 12 la teoría de las relaciones objetales, la cual dio prioridad al yo, haciéndolo el centro de la realidad del sujeto. Desde dicha perspectiva, se equipara al yo con una especie de conciencia, por lo que el tratamien
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En tanto que el sentido del t rmino
2018-10-25
En tanto que el sentido del término se fue vinculando con la posición que ocupa quien lo usa o con el deseo de ocupar una posición particular al usarlo, resultó muy rápida su adopción por los más diversos públicos. En un inicio, quienes más lo usaban eran mujeres feministas, académicas o militantes.
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Estas organizaciones decidieron dejar fuera los temas de hom
2018-10-25
Estas organizaciones decidieron dejar fuera los temas de homosexualidad y aborto, porque no estaban en el programa oficial; fue parte de una acción que apeló al derecho positivo, pues citaron todo un andamiaje jurídico nacional e internacional, ya que la educación sexual laica está respaldada en el
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br Domain specific survey of IoT
2018-10-25
Domain specific survey of IoT cloud platforms This section presents 26 IoT cloud platforms according to their appropriateness into the specific application domains. It is obvious that there are many more platforms present in the market, but due to tech-specific and time limits 26 of these are cho
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Mashamba et al found positive relationship between deposit
2018-10-25
Mashamba et al. (2014), found positive relationship between deposit interest rate and bank deposits in Zimbabwe. Sukmana and Kassim (2010) studies that any shock in interest rate will negatively impact the Islamic bank׳s deposit. Haron and Azmi (2006) work on deposit determinants of commercial ban
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br Materials and methods br
2018-10-24
Materials and methods Results Discussion Microglia are resident immune Myoseverin in the CNS that regulate innate immunity and participate in adaptive immune response (Hanisch and Kettenmann, 2007). However, the roles of microglia in AD pathology are still under debate. While there is signi
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The identification of stem cells or progenitor cells and
2018-10-24
The identification of stem R406 or progenitor cells, and their contribution to pancreatic regeneration remain controversial (Ziv et al., 2013; Burke and Tosh, 2012). The pancreas uses several regenerative mechanisms. Self-renewal is the principal mechanism of acinar and islet regeneration in respons
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In this work we have
2018-10-24
In this work, we have shown the dramatic effect of the loss of FMRP on the gene expression profile of neurons. In the absence of FMRP, the neural hsa-mir-382 levels are decreased, preventing the differentiation-dependent downregulation of REST. The resulting higher levels of REST in FXS-derived neur
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Cryopreserved peripheral blood mononuclear cells PBMC from t
2018-10-24
Cryopreserved peripheral blood mononuclear cells (PBMC) from this patient were used for the generation of an induced pluripotent stem cell (iPSC) that harbour a “highest risk” RET mutation according to ATA guidelines, i.e. a 2753T>C missense de novo mutation at exon 16 leading to the most frequent M
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nampt inhibitor br Acknowledgements This work was supported
2018-10-24
Acknowledgements This work was supported by the IRET Foundation (2015-2016), Ozzano Emilia, Italy (no-profit organization), in the frame of the “Step-by-step” POR-FESR 2016-2020 Emilia Romagna Region project. Introduction Resident neural stem cells (NSCs) persist in the adult mammalian centra
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To determine whether overexpression of Sca in progenitor
2018-10-24
To determine whether overexpression of Sca-1 in progenitor cells residing in the bulge and upper isthmus could function as an initiating event, Rosa:Cre mice and control littermates were treated with TPA only. This treatment resulted in very few papillomas that quickly regressed and there was no sig
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