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Considering the fact that OCL induced
2022-08-05
Considering the fact that OCL induced depletion of T BMX-IN-1 in non-stimulated cultures, the only possible explanation of this effect is the elevated mortality of these cells. It was found that OCL at the higher concentration induced the apoptosis of CD4+ and CD8+ T cells. These results strongly s
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Sertraline HCl sale New follicular wave emergence is associa
2022-08-05
New follicular wave emergence is associated closely with the stage of the estrous Sertraline HCl sale (Sirois and Fortune, 1988). As indicated by results from the present experiment, cows that had regression of the largest follicle on Day 0 of treatment onset had follicle wave characteristics that
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Based on the role of NMDA receptors in
2022-08-05
Based on the role of NMDA receptors in initiation and propagation of epileptic seizures and on potentiation of NMDA function by glycine, it has been hypothesized that glycine will have proconvulsant activity (Foster and Kemp, 1989). Indeed, there is some evidence that human epileptogenic foci, remov
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br Discussion CHO K cell lines stably expressing each
2022-08-05
Discussion CHO-K1 cell lines stably expressing each of the NH2-terminal isoforms of the human glycine reuptake transporter GlyT1 have been developed. GlyT1 uptake assays have been validated for two lines for each isoform, one low and high expressor. Expression levels in the lines have been confir
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br Material and methods br Result br Discussion The
2022-08-05
Material and methods Result Discussion The female with well-differentiated endometrial cancer, especially those in the reproductive age have a strong desire to preserve fertility. Therefore, conservative medical treatment with progestin is widely used in the clinic. However, up to 30% of pa
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br Author s contributions br Conflict of
2022-08-05
Author's contributions Conflict of interest Acknowledgements This work was supported in part by a grant from Department of Biotechnology (DBT), Government of India (Sanction Order No.: BT/563/NE/U-Excel/2016). MC, PDG and SKM acknowledge the Ministry of Human Resource and Development (MHRD)
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Although we showed that RBL
2022-08-05
Although we showed that RBL-2H3 Sc98 β-Sitosterol took up histamine from the microenvironment, it was unclear which transporter mediated its passage across the plasma membrane. Other biogenic amines have selective transporters that belong to the neurotransmitter sodium symporter family, including SE
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However Gingrich and Hen reported
2022-08-05
However, Gingrich and Hen reported that absence of the gene at all stages of ontogenesis of mice may interfere with the normal developmental program and/or the organism may undergo changes in other systems to compensate for gene absence (46). In addition, potentially altered maternal behavior of GPR
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br Funding sources This work was supported in part
2022-08-05
Funding sources This work was supported, in part, by NIH GM115388 to BGM. Acknowledgements Introduction Glucokinase (GCK) plays a central role in the regulation of glucose metabolism. Its activity is restricted to chk1 with important roles in whole-body glucose homeostasis [1]. In pancrea
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Glucagon was described as an insulin secretagogue as early
2022-08-05
Glucagon was described as an insulin secretagogue as early as 1965 (Samols et al., 1965). Our studies extend these findings by demonstrating that this is a direct effect mediated by distinct receptors in the mouse pancreas. Previous experiments on isolated β 51 8 clearly show that glucagon is capab
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br Hedgehog HH signaling plays
2022-08-05
Hedgehog (HH) signaling plays an important role both during embryonic development and adult life. It is involved in the regulation of cell differentiation, cell proliferation and tissue polarity, as well as in the maintenance of stem cells, tissue repair, and regeneration (, ). Three ligands, Indi
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Beside these studies related to food
2022-08-05
Beside these studies related to food, several groups examined the role of ghrelin in the actions of psychostimulants. Modulation of the ghrelin system and food restriction alter locomotor sensitization, DA release in the NAc, and CPP induced by cocaine, amphetamine, and nicotine (Abizaid et al., 201
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br Conclusion We have demonstrated
2022-08-04
Conclusion We have demonstrated that ETB receptors negatively regulate the expression of AT1 receptors in renal proximal tubule Metformin from WKY rats but not in SHRs. Short-term activation of the ETB receptor increases AT1 receptor phosphorylation in WKY cells but decreases it in SHR cells. We
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Dysregulation of catecholaminergic neurotransmission particu
2022-08-04
Dysregulation of catecholaminergic neurotransmission, particularly the dopaminergic system, has long been correlated with the development of neuroinflammation and HAND. Studies specifically examining role of catecholamines in HIV pathogenesis, particularly focused on NeuroHIV, are relatively few. Ho
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br Mammalian chromosomal DNA binds to
2022-08-04
Mammalian chromosomal DNA binds to various proteins and the DNA-protein complexes form DNA packaging units, called nucleosomes. Histones are the chief protein components of nucleosomes and perform pivotal functions in chromosomal gene regulation. Moreover, many types of chemical modifications of h
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