• Substituents at the C position An oxygen containing

  2021-02-24

  

  Substituents at the C11 position — An oxygen-containing substituent at the C11 position also affects the catalytic activity of Δ1-KSTDs. The Δ1-KSTDs from the Gram-positive bacteria R. equi [29], N. simplex ATCC 6946 and IFO 12069 [48,49,52], and R. rhodochrous IFO 3338 [27] were able to 1(2)-dehydr

• We further examined our hypothesis

  2021-02-24

  

  We further examined our hypothesis that the activation of CRF and CCK systems is responsible for the enhanced anxiety-like behavior induced by immobilization stress using two antagonists to block the expression of CRF1 and CCK2 receptors. It was found that CCK2 receptor antagonist CR2945 or CRF1 ant

• carbenicillin While showing that deletion of EP maintains

  2021-02-24

  

  While showing that deletion of EP1 maintains femur bone volume fraction and trabecular bone parameters during aging, perhaps more importantly we have also demonstrated that increased initial BV/TV in EP1 is protective against OVX-induced bone loss. That is, while mice lose an approximately equal pe

• br Conclusions br ISG is an

  2021-02-24

  

  Conclusions ISG15 is an ubiquitin‐like protein that is induced by treating mammalian AL 8810 with interferon‐α/β. UbE1L was identified as the E1‐activating enzyme for ISG15 in the course of experiments that demonstrated that the nonstructural or NS1 protein of influenza B virus inhibits ISG15

• More unusual modifications also regulate DUBs Recent reports

  2021-02-24

  

  More unusual modifications also regulate DUBs. Recent reports have illustrated how reactive oxygen species (ROS) can regulate DUB activity 87, 88, 89, 90. ROS can serve as potent signaling molecules by reacting with active site cysteines of tyrosine phosphatases and some cysteine peptidases to form

• In studies directed toward the development

  2021-02-24

  

  In studies directed toward the development of sequence-specific major-groove binding small A-674563 [11], we desired a non-intercalating molecular scaffold that could direct attached moieties into the major groove. As an initial step toward this goal, we wished to study the DNA binding mode and af

• The involvement of FOXO and STAT

  2021-02-24

  

  The involvement of FOXO3 and STAT5 in DNA-PKcs and Apicidin mg IV has not been reported before, and the search by the ECR browser (http://ecrbrowser.decode.org) revealed that 1kb of the 5′ promoter of DNA-PKcs possesses 4 STAT (−908bp to −901bp, −676bp to −656bp, −533bp to −526bp and −66bp to −59bp

• Acknowledgements This work was supported in part

  2021-02-23

  

  Acknowledgements This work was supported in part by a Scholarship Fund for Young Researchers by the Promotion and Mutual Aid Corporation for Private (2017 to S.K.), research grant from Japan Rett Syndrome Support Organization (2018 to S.K.), and MEXT-Supported Program for the Strategic Research Fou

• The identification of a functional leucine rich NES mediatin

  2021-02-23

  

  The identification of a functional leucine-rich NES mediating 8E7 nuclear export led us to analyze the interaction between 8E7 and CRM1 nuclear export receptor. HeLa cell lysates containing EGFP-8E7, EGFP–8cE7, EGFP-16E7–NES (as a positive control), or EGFP (as a negative control) were incubated wit

• In rats exposed to day of nicotine withdrawal

  2021-02-23

  

  In rats exposed to 1 day of nicotine withdrawal (24 h after the last nicotine administration) we expected a decrease of general locomotor activity and a decrease of global striatal dopamine release, which were assessed in a previous study following 14 days of nicotine exposure and 24 h of nicotine w

• The mechanisms in the central nervous

  2021-02-23

  

  The mechanisms in the central nervous system (CNS) controlling the sympathetic tone of the Emodepside australia are associated to behavioral strategies, such as those involved in response to stress. In this regard, morphine withdrawal induces profound and severe stress reactions evidenced by enhanc

• Cubic equations of state CEoS are particularly popular

  2021-02-23

  

  Cubic equations of state (CEoS) are particularly popular due to their simplicity and relatively good accuracy in predicting vapour-liquid equilibrium and liquid-liquid equilibrium for small, non-polar, non-associating molecules, such as light hydrocarbons. CEoS can match the phase boundaries (L/LL a

• A widely accepted mechanism to differentiate hESCs

  2021-02-23

  

  A widely accepted mechanism to differentiate hESCs into cardiomyocytes is through perturbation of the canonical Wnt/β-catenin pathway. Initial Wnt activation is required to form the Rat Erythropoietin / EPO Protein (His Tag) [3]. Thereafter, it is believed that inhibition of the canonical Wnt/β-ca

• HA activates its receptor channels to cause an

  2021-02-23

  

  HA activates its receptor channels to cause an inward chloride flux in the insect nervous system (Hardie, 1989). Two genes encoding the subunits of these channels were first identified in D. melanogaster: one previously known as ort (also differently named as hclA, DM-HisCl-α1, hisCl2 and Dm HA-Cl I

• In conclusion the results obtained in this study and those

  2021-02-23

  

  In conclusion, the results obtained in this study and those recently reported by our group (Abdel-Samad et al., 2012) clearly indicate that a dialogue indeed exists between the systems of NPY and ET-1 at the level of human endocardial endothelial cells, since these cells, whether isolated from the r

11293 records 387/753 page Previous Next First page 上5页 386387388389390 下5页 Last page