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br The LSCP model and
2020-03-10
The LSCP model and its properties In this section, we first introduce the LSCP model in Section 2.1. Some examples of the model are presented in Section 2.2 and basic properties of the model are presented in Section 2.3. Finally, Section 2.4 introduces finite dimensional approximations necessary
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The final test that was performed was to determine
2020-03-10
The final test that was performed was to determine whether the trigger points of the current limiters are stable across a wide temperature range. This test was performed within a thermal-vacuum chamber on each current limiter individually. All the current limiter trip currents were set to approximat
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More recently it was discovered that BChE
2020-03-09
More recently, it was discovered that BChE hydrolyzes the neuropeptide gut hormone, ghrelin [25], [26], [27], [28]. Nonetheless, because the enzyme reaction is very slow, those who first reported this finding were initially reluctant to attribute a real physiological role for that phenomenon. Our ow
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br Effects of estrogens on bone Estrogens play
2020-03-09
Effects of estrogens on bone Estrogens play an important role in bone remodeling, as demonstrated by studies in mice in which the ER genes were deleted [21], [22]. ERβ compensates for the rna polymerase ii of ERα, and vice versa, but when both ERs are deleted a profound decrease in trabecular bo
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Enzyme selectivity of many enzymes like galactosidases acyla
2020-03-09
Enzyme selectivity of many rho kinase inhibitor like β-galactosidases, acylases, epoxyhydrolases, lipases, etc. has also been modulated by using different immobilization techniques. It can result in the selection of optimal biocatalyst for different processes. This has many advantages over strategi
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Structure similarity searches were conducted using
2020-03-09
Structure similarity searches were conducted using the standalone version of the DALI program with the query structures scanned against a local current version of the PDB that has all chains as separate entries (Holm and Sander, 1995). The structural hits for each query were collected, even if the D
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The lack of robust immunocompetent animal models permissive
2020-03-09
The lack of robust immunocompetent animal models permissive for HCV makes it hard to assess if the quantity and quality of vaccine-induced immunity is sufficient to confer protection. Thus, it is difficult to predict to what extent antibody responses induced by current vaccination approaches, includ
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br Materials and methods br Results
2020-03-09
Materials and methods Results Discussion The 5-HT2A and D2 receptors have a functional crosstalk (Albizu et al., 2011) and they TCS 2002 are all richly expressed in the mesolimbic and mesocortical systems (Azmitia and Segal, 1978; McMahon et al., 2001), providing the neuroanatomical basis
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The most important finding in
2020-03-09
The most important finding in the present study is that the EKR1/2-Egr-1 signaling pathway might be involve in the mechanisms underlying CysLT2 receptor-mediated IL-8 production. The signaling profile can be described by the following sequential processes: the agonists (LTC4 and LTD4) activates CysL
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benzydamine br CDK Inhibitors for the Treatment of inflammat
2020-03-09
CDK Inhibitors for the Treatment of inflammatory Diseases Several CDKs have been implicated as regulators of inflammatory gene expression. It will thus be very important to determine the relative contributions of the various CDKs and their kinase function on a systematic basis. This work will be
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As the principal receptors for regulating the
2020-03-09
As the principal receptors for regulating the inflammatory process in mammals, CXCR1 and CXCR2 have an important role in regulating the trafficking of phagocytes such as neutrophils, monocytes and macrophages (Viola and Luster, 2008). The evidence gathered to date from fish studies are in agreement
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As DNA methylation plays a critical role in organismic
2020-03-07
As DNA methylation plays a critical role in organismic development and human diseases, the interest in DNA methyltransferases is constantly increasing. Extensive studies on the repertoires of dnmts genes have indicated increasing dnmts members in eukaryotes (Goll and Bestor, 2005; Ponger and Li, 200
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Enterobacteriaceae are gram negative rods
2020-03-07
Enterobacteriaceae are gram negative rods that include the Escherichia coli and Shigella. There are several DNA ligases posted on the GenBank belong mostly to Enterobacteria phages, such as the T4 bacteriophage [30]. There are several protein markers used to differentiate between T4 phage superfamil
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During the past three decades platinum based DNA
2020-03-07
During the past three decades, platinum-based DNA-alkylating agents have been employed in the treatment of various cancers [14]. Oxaliplatin is currently used as a first-line treatment for colorectal cancer (CRC) [15]. Unfortunately, a large portion of CRC patients receiving oxaliplatin-based chemo
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Interestingly global EGFR depletion increased the rate
2020-03-07
Interestingly, global EGFR depletion increased the rate of cell elimination everywhere in the notum (Figures 2B–2D), irrespective of the deformation status of the cells. Accordingly, we found that nop receptor are not any more sensitive to stretching upon EGFR depletion (Figures S6A–S6C; Video S5).
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