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Importance of heart failure Acute decompensated heart failur
2019-05-17
Importance of jak inhibitor failure Acute decompensated heart failure (ADHF) refers to a clinical condition of worsening HF with dyspnea, often with evidence of fluid overload [1]. This is generally triggered by 1 of the 4 main factors: atrial fibrillation, anemia, hypertension, and medication/diet
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br Discussion GISTs originate from the interstitial cells of
2019-05-17
Discussion GISTs originate from the interstitial glutathione s-transferase of Cajal. They occur commonly in the stomach (50–60%), the small intestine (30–35%), the colon and rectum (5%) and the esophagus (exon 11 is also associated with frequent tumor recurrence than with a PDGFRA mutation. Lat
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In the phase AZURE trial
2019-05-17
In the phase 3 AZURE trial, 3360 women were randomly assigned to receive standard adjuvant systemic treatment alone (control group) or with 4mg intravenous zoledronic baicalein every 3–4 weeks for 6 doses, then every 3 months for 8 doses, followed by every 6 months for 5 doses, for a total of 5 yea
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HRU resulting from SREs is of increasing relevance in
2019-05-17
HRU resulting from SREs is of increasing relevance in times of financial and economic restraint because it can help to determine the financial burden to hospital managers and payers. A separate analysis of the costs associated with SREs in this study found that the most costly SRE, spinal cord compr
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Both breast cancer and MM cause osteolytic lesions inhibitin
2019-05-17
Both breast cancer and MM cause osteolytic lesions, inhibiting osteoblast differentiation and thereby tipping the balance in favour of osteoclastic activity. In contrast, prostate cancer predominantly causes osteoblastic bone disease. Interestingly, increased marrow adiposity has been associated wit
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br Discussion We describe an additional
2019-05-17
Discussion We describe an additional diagnosis to consider when BVT is identified. One of the proposed mechanisms of BVT include elevated intracellular calcium, causing delay after depolarization in anatomically separate parts of the conducting system. Baher et al. [1] proposed that two separate
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El cap tulo sobre de Jos Agust n expone
2019-05-17
El capítulo sobre de José Agustín expone las diferencias entre el de Agustín, de 1966, y el de Pacheco, de 1972. Lo que tienen en común ambas obras, aclara el crítico, es que —a diferencia de otras estudiadas en el volumen— no atestiguan momentos de crisis sino “los largos entretiempos que precede
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br Results and discussion In
2019-05-16
Results and discussion In this study, the np9 and gag mRNA expression was established for 25 patients with CLL (Fig. 1). We found that the transcriptional activity of HERV-K np9 gene in CLL patients was higher than in PBMCs from healthy donors. The results revealed that 18 out of 25 CLL patients
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Cell adhesion to extracellular matrix requires the interacti
2019-05-16
Cell adhesion to extracellular matrix requires the interaction of different molecules like selectins, cadherins and integrins [21]. Especially αvβ3 integrin has been proposed to mediate the adhesion of malignant cells in different entities such as multiple myeloma and breast cancer [22,23]. Upon exp
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br Therapy for the CPVT br Conflict
2019-05-16
Therapy for the CPVT Conflict of interest Acknowledgment This work was supported by Health Science Research grant from the Ministry of Health, Labour and Welfare of Japan for Clinical Research on Measures for Intractable Diseases (2016-032). Introduction Bradyarrhythmia is a serious ele
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substance p cost No conviene ignorar la enorme influencia
2019-05-16
No conviene ignorar la enorme influencia cultural de Estados Unidos en la formación intelectual de Vasconcelos, so pena de caer en contradicciones. Ulises criollo se asienta en una tradición muy estadounidense, la de una fascinación por las cuestiones de la individualidad, la identidad y la autobiog
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rxr receptor Introduction Atrial fibrillation AF is the most
2019-05-16
Introduction Atrial fibrillation (AF) is the most common arrhythmia in adults and the most common cause of embolic stroke. AF affects approximately 0.8 million patients in Japan alone, and its incidence is expected to grow exponentially [1–3]. However, the electrophysiological mechanisms of the ini
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Hereditary syndromes with increased risk for gastric cancer
2019-05-16
Hereditary syndromes with increased risk for gastric cancer include: 1) hereditary diffuse gastric cancer, 2) Lynch syndrome/hereditary non-polyposis colorectal cancer, 3) juvenile polyposis syndrome, 4) Peutz-Jeghers syndrome and 5) familial adenomatous polyposis. Hereditary diffuse gastric cancer
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br Patients and methods br Discussion In
2019-05-16
Patients and methods Discussion In this buy Doxorubicin HCl secondary endpoint analysis of the OPTION trial, we have shown that the addition of goserelin to neo(adjuvant) chemotherapy temporarily increased bone turnover during treatment and that this reverses over the next 6–12 months after co
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br de Hern n Lara Zavala se suma
2019-05-16
de Hernán Lara Zavala se suma al acervo literario de novelas históricas de México. En los albores del México independiente, la novela histórica representó una vía de exploración y defini-ción del “ser nacional”. A casi dos siglos de distancia la novela histórica ocupa un lugar central en la produc
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