• Maldovanu and Sela designed a competition model with

  2018-11-15

  

  Maldovanu and Sela (2006) designed a p2x7 receptor model with elimination stages. The effort\'s cost function includes an ability parameter that is private information for each competitor. The authors show that when the cost is a concave (or linear) function of effort, the equilibrium total expecte

• The concept of personalised medicine

  2018-11-15

  

  The concept of personalised medicine is not new, however the rapid advances in technologies such as genomics, transcriptomics and metabolomics for the analysis of blood and tissue has opened up new horizons in this area in the last few years (). As outlined above, the range of biotherapeutics now av

• br Material and methods br Results

  2018-11-15

  

  Material and methods Results Discussion To our knowledge, our study is the first VBM study to report a gender-by-diagnosis interaction in individuals with ADHD. The interaction effect was found in the ventral ACC, where girls with ADHD showed increased GM volumes when compared to TD girls,

• What is more contrary to hypothesis mean activity was

  2018-11-15

  

  What is more, contrary to hypothesis (5), mean activity was also negatively correlated with trait anxiety in the superior PFC (Fig. 4, bottom right). So, trait anxiety was negatively correlated with prefrontal and positively with visual cortical activity. Consistently, in adolescents suffering from

• Taken together studies of both neuroanatomy and neural funct

  2018-11-15

  

  Taken together, studies of both neuroanatomy and neural functional activation yield SES-related differences in BMN673 regions that support language; these findings, however, have not reliably been linked to differences in language functioning. Importantly, a recent study has shown no measurable dif

• br Acknowledgments br Introduction Keratoacanthoma centrifug

  2018-11-15

  

  Acknowledgments Introduction Keratoacanthoma centrifugum marginatum (KCM) is a rare variant of keratoacanthoma (KA) and is characterized by multiple KAs with progressive peripheral growth and simultaneous central healing. KCM was first described by Miedzinski and Kozakiewicz in 1962 and the na

• As for the acantholysis the

  2018-11-15

  

  As for the acantholysis, the patient had negative direct immunofluorescence and indirect immunofluorescence studies, which exclude autoimmune bullous diseases. In addition to keratinocyte injury induced shedding, exfoliative toxin A produced by targets desmoglein 1 and may cause acantholysis. Moreov

• br Case presentation A year old female visited

  2018-11-15

  

  Case presentation A 25-year-old female visited our outpatient clinic in April 2013 with badly decayed teeth. Careful intraoral and extraoral examinations revealed xerostomia, candidal infection on her tongue, difficulty in swallowing and parotidomegaly (Fig. 1). Familial sociological profile of t

• The increasing number of studies

  2018-11-14

  

  The increasing number of studies focusing on regenerative medicine and stem cell transplantation is being accompanied by the development of techniques using many types of nanoparticles. The combination of nanotechnology with stem cell research may be able to address some challenges in this research

• atm inhibitor Gregg and Weiss demonstrated that intraventric

  2018-11-14

  

  Gregg and Weiss (2003) demonstrated that intraventricular injection of EGF and TGF-α induces the generation of RGLCs in the SVZ in adult mice. Zhou et al. (2001) demonstrated that TGF-α induces, in vitro, the differentiation of mature astrocytes into radial cells. We analyzed the levels of TGF-α mRN

• br Results br Discussion Here we describe the identification

  2018-11-14

  

  Results Discussion Here, we describe the identification of an epigenetic mechanism necessary and sufficient to maintain pluripotency and/or avoid precocious differentiation of the germ cell lineage in C. elegans. Histone H3K4 demethylase SPR-5/LDS1 physically interacts with the LET-418-contain

• br Results br Discussion In

  2018-11-14

  

  Results Discussion In previous studies, we derived pericytes (Kusuma et al., 2013) and both hiPSC syn-vSMCs and hiPSC con-vSMCs (Wanjare et al., 2013a). In performing direct comparisons between these perivascular cell derivatives, we observed numerous differences that enable the study of human

• The first bleeding risk prediction

  2018-11-14

  

  The first bleeding risk prediction score (ORBI score) was published in 1998 and it was developed in patients newly started on warfarin after hospitalisation for venous thromboembolism (Beyth et al., 1998). Since then various bleeding risk scores have been described but only four (HAEMORR2AGES (Gage

• br Authors Contributions br Declaration of Interests

  2018-11-14

  

  Authors\' Contributions Declaration of Interests Ethics Committee Approval Acknowledgements SCa is partly funded by ANR grant no. ANR-11-DPBS-0002. The DEFI study was supported by a national program for clinical research (PHRC 2005) (AOM05018) and by the National Centre for Hereditary

• Besides our strongest GWAS signal we

  2018-11-14

  

  Besides our strongest GWAS signal, we also found association signals which have previously been associated with complex diseases including sepsis phenotypes. Genomic variation in CRISPLD2 was reported to be associated with the presence of cleft lips (Mijiti et al., 2015), and recent work showed a de

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