• To determine whether overexpression of Sca

  2018-11-08

  

  To determine whether overexpression of Sca-1 in progenitor cells residing in the bulge and upper isthmus could function as an initiating event, Rosa:Cre mice and control littermates were treated with TPA only. This treatment resulted in very few papillomas that quickly regressed and there was no sig

• As an initial application of our RNA

  2018-11-08

  

  As an initial application of our RNA-seq datasets for discovery of regulatory mechanisms in huSCs, we compared transcriptomes of quiescent huSCs to those of activated huSCs to identify loci that were differentially expressed. In quiescent huSCs, we identified 998 highly expressed genes, including 13

• In mammalian PGCs genetic knockout

  2018-11-08

  

  In mammalian PGCs, genetic knockout models and short-term PGC culture experiments have implicated the growth factors BMP4, LIF, SCF, retinoic acid, and FGF in early survival and proliferation (Dolci et al., 1991, 1993; Farini et al., 2005; Matsui et al., 1991). PGCs isolated from mammalian species c

• Disease modeling with iPSCs can be challenging due

  2018-11-08

  

  Disease modeling with iPSCs can be challenging due to inherent patient variability and line-to-line differences (Hu et al., 2010; Boulting et al., 2011). Importantly, very few differences were observed among the three independent control lines. The SNCA (3×) iPSC line was not different from controls

• br Results br Discussion Although cell therapy is a promisin

  2018-11-07

  

  Results Discussion Although cell therapy is a promising approach for treating enteric neuropathies, it is commonly thought that enteric neural progenitors isolated from the human bowel will require biological and/or genetic manipulation prior to transplantation, owing to the size of the human

• Another major goal of this

  2018-11-07

  

  Another major goal of this study was to evaluate the significance of multiple measures of Wortmannin for shaping black-white disparities in physical health. Our results show that black-white differences in allostatic load vary by blacks’ skin tone. Specifically, with both self-identified race and i

• The relationship between physical activity race ethnicity an

  2018-11-07

  

  The relationship between physical activity, race/ethnicity, and income is complex, and differs depending on physical activity domain (e.g., leisure activity versus active transportation; Kruger, Ham, Berrigan, & Ballard-Barbash, 2008), age group (Cain et al., 2014), neighborhood type (urban versus s

• The model represents the first serious effort

  2018-11-07

  

  The 1972 model represents the first serious effort made by Lucas to construct a stochastic general equilibrium model, grounded on a sound microeconomic basis (i.e., a perfect fexofenadine hydrochloride framework, rational agents in Muth\'s sense, and continuous market clearing), capable of mimickin

• The existence of sex differences

  2018-11-07

  

  The existence of sex differences in the response to caffeine in young subjects have been studied in humans [8,20] and rodents [21–23], with different conclusions. Soellner et al. [24] reported improved object-discrimination in female rats, following caffeine ingestion. Elkins et al. [20], looking at

• La integraci n se promov

  2018-11-07

  

  La integración se promovía fundamentalmente chemokine receptor través del comercio de mercancías, no se incluía el comercio de servicios, ni las compras gubernamentales, o la propiedad intelectual y la legislación nacional limitaban la inversión extranjera directa (ied); aunque se fomentaba la crea

• purchase IWR-1-endo br Determinaci n de la elasticidad del g

  2018-11-07

  

  4. Determinación de la elasticidad del gasto Para obtener la elasticidad del gasto en Salud de los hogares con y sin remesas se procedió purchase IWR-1-endo realizar una regresión con factor de interacción (Cuadro 5), y cuyos parámetros resultaron significativos a un nivel de confianza del 95%.

• Our simulation model provides an independent confirmation of

  2018-11-07

  

  Our simulation model provides an independent confirmation of the CMV doubling time we estimated. The model derives a proportion of CMV infections diagnosed with an undesirably high CMV viral load when screening the cohort every 7days to be comparable with what we actually observe in our cohort. With

• Declaration of Interest The author s department

  2018-11-07

  

  Declaration of Interest The author\'s department has received funding from the National Institute for Health Research (ref 11/46/14) for a pandemic influenza clinical trial and unrestricted investigator-initiated research funding from Pfizer (ref WI179623) for a study on pneumonia. Annually in t

• Previous research has shown that c myc

  2018-11-07

  

  Previous research has shown that c-myc acts as a key regulator of hTERT transcription during carcinogenesis via its binding to the E-box (Enhancer Box) and subsequent activation of transcription (Kyo et al., 2008). Therefore, one underlying mechanism for MEHP contribution to telomere length maintena

• Of note of the cloned mABs from

  2018-11-07

  

  Of note, 40–60% of the cloned mABs from sorted IgG MBC-DENV cells were found to specifically bind to DENV (Fig. 4B) and this validated our sorting strategy. None of the IgG MBC CDR3 sequences, however, were shared with the PB repertoire. We observed that memory B cell-derived, complex epitope-speci

14971 records 982/999 page Previous Next First page 上5页 981982983984985 下5页 Last page