• More and more studies are focused on

  2020-04-29

  

  More and more studies are focused on the function role of EPAC1 in cancer proliferation, apoptosis and migration. Recently, it was reported that the EPAC-ERK and AKT signaling pathways promote the B cell antigen receptor (BCR) mediated growth arrest and apoptosis in the B lymphoma cell line WEHI-231

• Future advances in the in vivo

  2020-04-29

  

  Future advances in the in vivo molecular imaging of enzyme activity will greatly benefit from the progress towards the quantitative detection of enzymes. Quantitative imaging requires knowledge of both the location and concentration of a specific enzyme, which is dependent on the simultaneous measur

• After crown formation root development begins via the intera

  2020-04-29

  

  After crown formation, root development begins via the interaction between the Hertwig root sheath (HERS) and the dental papilla, which differentiates into odontoblasts and forms dentin and pulp. HERS is associated with the number of roots and their morphology . The stem cells from the apical papill

• In pregnancy maternal uterine spiral

  2020-04-29

  

  In pregnancy, maternal uterine spiral artery (SA) remodeling is essential for ensuring efficient blood flow to the developing fetus. A subset of CD49a+Eomes+ decidual NK prolyl hydroxylase inhibitor (dNK) that actively secretes GFs, such as pleiotrophin and osteoglycin, have recently been described

• Currently two approaches can be used individually or combine

  2020-04-29

  

  Currently, two approaches can be used individually or combinedly to overcome weak immunogenicity of subunit smad inhibitor (Bookstaver et al., 2018; Moyle, 2017; Vartak and Sucheck, 2016). The first is to design particulate antigens. Virus-like particles (VLPs), for example—mainly derived from the

• Lithium Citrate br Role of cysLT signaling

  2020-04-29

  

  Role of cysLT signaling on various neurological complications which are associated with Alzheimer’s disease Alzheimer’s disease, first described in 1906 by Alois Alzheimer, is a neurodegenerative disease and a very common cause of dementia progressively leading to death. Even though years of rese

• By using the C elegans Matrisome

  2020-04-29

  

  By using the C. elegans Matrisome Annotator tool, we found substantial enrichment for matrisome Tankyrase Inhibitors 22 in these data sets. Thus, re-analyzing -omic datasets with the C. elegans Matrisome Annotator tool may be useful to generate novel hypotheses about the role of the C. elegans matr

• From the results of previous experiments with the purvalanol

  2020-04-29

  

  From the results of previous experiments with the purvalanol B affinity matrix, it is not clear whether the selective capture of parasite CK1 enzymes is a reflection of their high abundance or rather their affinity for the ligand compared with other kinases present in the lysates. Based on compariso

• Assessment of DNA damage by comet

  2020-04-29

  

  Assessment of DNA damage by comet assay and ChEs activity has been widely used as a biomarker of genotoxicity and exposure to pesticide respectively, to measure the risk related to pesticides in the exposed population [15]. Very few studies have explored the association between DNA damage and worker

• br Introduction The dopaminergic system and its projections

  2020-04-28

  

  Introduction The dopaminergic system and its projections including both the prefrontal Epalrestat (PFC) and striatum are known as being crucial to synaptic plasticity, skill acquisition and higher order functions (e.g., working memory and cognitive control; Matsumoto et al., 2003). Variations in

• DUBs are involved in cell cycle

  2020-04-28

  

  DUBs are involved in at the end of your rope regulation and DNA damage pathways and since, in cancer and different stress conditions all the proteins which regulate cell cycle and DNA damage/repair are either up/down regulated (Singh et al., 2013, Singh et al., 2011, Kumar and de Massy, 2010, Gupta

• DPP is show two relevant benefits

  2020-04-28

  

  DPP-4is show two relevant benefits in the clinical management of type 2 diabetic patients: negligible risk of severe hypoglycemia, particularly when compared with sulphonylureas [[33], [34]], and weight neutrality, in contrast with the weight gain generally observed with insulin therapy, sulfonylure

• Both meiotic COs and NCOs require DNA synthesis current

  2020-04-28

  

  Both meiotic COs and NCOs require DNA synthesis, current data from sequencing also suggest that COs require more DNA synthesis than NCO 63., 64., 65.. However, analysis of the role of DNA synthesis in NCOs remains relatively uncharacterized. Emerging evidence points to a role for either Polδ or Polε

• Introduction In vitro synthetic biology has received conside

  2020-04-28

  

  Introduction In vitro synthetic biology has received considerably less attention than in vivo processes so far (Foster and Church, 2007). However, cell-free biosynthetic production is very likely to become important for many biotechnological challenges for reasons such as (energy) efficiency, syste

• Except for S adenosylmethionine SAM Fig sources of endogenou

  2020-04-28

  

  Except for S-adenosylmethionine (SAM, Fig. 1), sources of endogenous DNA alkylation are not well defined. Other possible sources include nitroso compounds related to the well known mutagen methylnitrosourea which are generated in vitro by nitrosation of cellular amines including amino acids, protein

11422 records 543/762 page Previous Next First page 上5页 541542543544545 下5页 Last page